Styx Gene Summary [Mouse]

Predicted to enable F-box domain binding activity and pseudophosphatase activity. Acts upstream of or within spermatogenesis. Located in cytoplasm. Orthologous to human STYX (serine/threonine/tyrosine interacting protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Styx
Official Name
serine/threonine/tyrosine interaction protein [Source:MGI Symbol;Acc:MGI:1891150]
Ensembl ID
ENSMUSG00000053205
Bio databases IDs NCBI: 56291 Ensembl: ENSMUSG00000053205
Aliases serine/threonine/tyrosine interaction protein
Synonyms 0610039A20Rik, hStyxb, LOC730432, serine/threonine/tyrosine interacting protein, serine/threonine/tyrosine interaction protein, STYXB
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Styx often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Dual specificity phosphatase, catalytic domain
  • Protein tyrosine phosphatase, catalytic domain, undefined specificity
  • pseudophosphatase
  • phosphatase
  • protein domain specific binding
  • protein binding
  • PTP_DSP_cys
  • Protein tyrosine phosphatase, catalytic domain motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • asthenozoospermia
regulated by
  • dexamethasone
  • rifampin
  • ritonavir
  • troglitazone
  • IGF2BP1
  • UCP1
regulates
role in cell
  • development
  • differentiation
  • binding in
  • migration
  • abnormal morphology
  • morphology
  • production
  • polarization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • perinuclear region
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Styx gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of ERK1 and ERK2 cascade
  • negative regulation of protein binding

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • pseudophosphatase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.