DCAF12L1 Gene Summary [Human]
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | DCAF12L1 |
| Official Name | DDB1 and CUL4 associated factor 12 like 1 [Source:HGNC Symbol;Acc:HGNC:29395] |
| Ensembl ID | ENSG00000198889 |
| Bio databases IDs | |
| Aliases | DDB1 and CUL4 associated factor 12 like 1 |
| Synonyms | DDB1 and CUL4 associated factor 12 like 1, KIAA1892L, WDR40B |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DCAF12L1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DCAF12L1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- CUL4 RING ubiquitin ligase complex
Molecular Function
What the gene product does at the molecular level
- protein binding