KLK9 Gene Summary [Human]

The protein encoded by this gene is a kallikrein-related serine protease. This gene is activated by steroid hormones in a human breast cancer cell line, making it a good marker for cancer detection. The encoded protein is found primarily in the cytoplasm.[provided by RefSeq, Oct 2010]

Details

Type
Protein Coding
Official Symbol
KLK9
Official Name
kallikrein related peptidase 9 [Source:HGNC Symbol;Acc:HGNC:6370]
Ensembl ID
ENSG00000213022
Bio databases IDs NCBI: 284366 Ensembl: ENSG00000213022
Aliases kallikrein related peptidase 9
Synonyms 1200016C12RIK, kallikrein related-peptidase 9, KLK-L3, Klnf
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KLK9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • tissue kallikrein
  • trypsin
  • Tryp_SPc
  • peptidase

Pathways

Biological processes and signaling networks where the KLK9 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • psoriasis
  • papilloma
  • papillomatosis
regulated by
role in cell
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human KLK9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • secretory granule
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • serine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.