CASTOR2 Gene Summary [Human]
Enables identical protein binding activity. Involved in negative regulation of TORC1 signaling. Located in cytosol. Colocalizes with GATOR2 complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CASTOR2 |
| Official Name | cytosolic arginine sensor for mTORC1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:37073] |
| Ensembl ID | ENSG00000274070 |
| Bio databases IDs | |
| Aliases | cytosolic arginine sensor for mTORC1 subunit 2 |
| Synonyms | 7530428J21Rik, Cytosolic arginine sensor for mTORC1 subunit 2, Gats, GATSL1, GATSL2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CASTOR2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain
- protein binding
- identical protein binding
- ACT domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CASTOR2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- arginine binding
- identical protein binding
- protein binding