Castor2 Gene Summary [Mouse]

Predicted to enable identical protein binding activity. Predicted to be involved in cellular response to L-arginine and negative regulation of TORC1 signaling. Predicted to be part of GATOR2 complex. Predicted to be active in cytosol. Orthologous to several human genes including CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Castor2
Official Name
cytosolic arginine sensor for mTORC1 subunit 2 [Source:MGI Symbol;Acc:MGI:1933384]
Ensembl ID
ENSMUSG00000015944
Bio databases IDs NCBI: 80909 Ensembl: ENSMUSG00000015944
Aliases cytosolic arginine sensor for mTORC1 subunit 2
Synonyms 7530428J21Rik, Cytosolic arginine sensor for mTORC1 subunit 2, Gats, GATSL1, GATSL2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Castor2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain
  • protein binding
  • identical protein binding
  • ACT domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Castor2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • arginine binding
  • identical protein binding
  • protein binding