Prdx1

Enables identical protein binding activity. Acts upstream of with a negative effect on canonical NF-kappaB signal transduction and regulation of non-canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including natural killer cell mediated cytotoxicity; regulation of stress-activated MAPK cascade; and removal of superoxide radicals. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Orthologous to human PRDX1 (peroxiredoxin 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prdx1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Prdx1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Prdx1 gene, providing context for its role in the cell.