Scpep1 Gene Summary [Mouse]
Enables serine-type carboxypeptidase activity. Involved in negative regulation of blood pressure. Acts upstream of or within blood vessel diameter maintenance. Predicted to be located in extracellular region. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; gut; and musculature. Orthologous to human SCPEP1 (serine carboxypeptidase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Scpep1 |
| Official Name | serine carboxypeptidase 1 [Source:MGI Symbol;Acc:MGI:1921867] |
| Ensembl ID | ENSMUSG00000000278 |
| Bio databases IDs | |
| Aliases | serine carboxypeptidase 1 |
| Synonyms | 2410018F01Rik, 4833411K15Rik, HSCP1, MSTP034, RISC, RISC1, serine carboxypeptidase 1, SERINE CARBOXYPEPTIDASE1 precursor |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Scpep1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PLN02209
- serine-type carboxypeptidase
- peptidase
- Serine carboxypeptidase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- perinuclear region
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Scpep1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- retinoic acid metabolic process
- negative regulation of blood pressure
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- serine-type carboxypeptidase activity