Atp5pb Gene Summary [Mouse]
Predicted to contribute to ATP hydrolysis activity and proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrial inner membrane and myelin sheath. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human ATP5PB (ATP synthase peripheral stalk-membrane subunit b). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atp5pb |
| Official Name | ATP synthase peripheral stalk-membrane subunit b [Source:MGI Symbol;Acc:MGI:1100495] |
| Ensembl ID | ENSMUSG00000000563 |
| Bio databases IDs | |
| Aliases | ATP synthase peripheral stalk-membrane subunit b |
| Synonyms | ATP5F1, ATP synthase peripheral stalk-membrane subunit b, LOC100911417, PIG47 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atp5pb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- adenosine-tetraphosphatase
- binding protein
- F-type ATP synthase, membrane subunit b
- protein binding
- hydrogen-transporting ATP synthase activity, rotational mechanism
- ATPase
- transporter
Pathways
Biological processes and signaling networks where the Atp5pb gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- myelin enriched fraction
- pH resistant lipid raft fraction
- detergent resistant lipid raft fraction
- cristae-like membrane
- cellular membrane
- Mitochondria
- myofilaments
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atp5pb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- substantia nigra development
- mitochondrial ATP synthesis coupled proton transport
- ATP synthesis coupled proton transport
Cellular Component
Where in the cell the gene product is active
- mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
- nucleus
- mitochondrial matrix
- membrane
- mitochondrion
- mitochondrial inner membrane
- mitochondrial proton-transporting ATP synthase complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- hydrogen ion transporting ATP synthase activity, rotational mechanism