Tubgcp3 Gene Summary [Mouse]
Predicted to enable gamma-tubulin binding activity. Predicted to contribute to microtubule minus-end binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule cytoskeleton. Predicted to be part of gamma-tubulin complex. Is expressed in cerebral cortex; metanephros; and thymus primordium. Orthologous to human TUBGCP3 (tubulin gamma complex component 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Tubgcp3 |
| Official Name | tubulin, gamma complex associated protein 3 [Source:MGI Symbol;Acc:MGI:2183752] |
| Ensembl ID | ENSMUSG00000000759 |
| Bio databases IDs | |
| Aliases | tubulin, gamma complex associated protein 3 |
| Synonyms | 104p, ALP6, GCP3, Grip104, SPBC98, Spc98, Spc98p, tubulin gamma complex component 3, tubulin, gamma complex component 3, tubulin γ complex component 3, tubulin, γ complex component 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tubgcp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- gamma-tubulin binding
- protein binding
- Gamma tubulin complex component N-terminal
- Gamma tubulin complex component C-terminal
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- centriole
- microtubules
- midbody
- cytosol
- polar microtubule
- mitotic spindle
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tubgcp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spindle assembly
- meiotic cell cycle
- microtubule nucleation
- cytoplasmic microtubule organization
- single fertilization
- mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasm
- centriole
- polar microtubule
- membrane
- equatorial microtubule organizing center
- spindle
- cytosol
- gamma-tubulin complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule minus-end binding
- structural molecule activity
- gamma-tubulin binding
- structural constituent of cytoskeleton