Tcea3 Gene Summary [Mouse]
Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including apical ectodermal ridge; early conceptus; genitourinary system; retina; and tongue. Orthologous to human TCEA3 (transcription elongation factor A3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Tcea3 |
| Official Name | transcription elongation factor A (SII), 3 [Source:MGI Symbol;Acc:MGI:1196908] |
| Ensembl ID | ENSMUSG00000001604 |
| Bio databases IDs | |
| Aliases | transcription elongation factor A (SII), 3 |
| Synonyms | S-II, SII-K1, TFIIS, TFIISH, TFIIS.H, transcription elongation factor A3, transcription elongation factor A (SII), 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tcea3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Transcription factor S-II (TFIIS), central domain
- TFIIS helical bundle-like domain
- TFIIS_I
- Zn-ribbon
- protein binding
- transcription elongation factor S-II
- Transcription factor S-II M domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tcea3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription, DNA-dependent
- transcription elongation from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- zinc ion binding
- protein binding