Abhd3 Gene Summary [Mouse]
Predicted to enable carboxylic ester hydrolase activity. Involved in phosphatidylcholine metabolic process. Predicted to be located in membrane. Is expressed in several structures, including brain; genitourinary system; liver; olfactory epithelium; and spleen. Orthologous to human ABHD3 (abhydrolase domain containing 3, phospholipase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Abhd3 |
| Official Name | abhydrolase domain containing 3 [Source:MGI Symbol;Acc:MGI:2147183] |
| Ensembl ID | ENSMUSG00000002475 |
| Bio databases IDs | |
| Aliases | abhydrolase domain containing 3 |
| Synonyms | abhydrolase domain containing 3, abhydrolase domain containing 3, phospholipase, LABH3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Abhd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alpha/beta hydrolase fold
- phospholipase A1
- alpha/beta hydrolases
- Alpha/beta hydrolase family
- enzyme
- phospholipase A2
Pathways
Biological processes and signaling networks where the Abhd3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Abhd3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phosphatidylcholine metabolic process
- medium-chain fatty acid biosynthetic process
- medium-chain fatty acid catabolic process
- phosphatidylcholine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- phospholipase A2 activity
- acylglycerol lipase activity
- 1-acyl-2-lysophosphatidylserine acylhydrolase activity
- acetylesterase activity
- phosphatidylserine 1-acylhydrolase activity
- phosphatidylcholine 1-acylhydrolase activity