ABHD3 Gene Summary [Human]

This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
ABHD3
Official Name
abhydrolase domain containing 3, phospholipase [Source:HGNC Symbol;Acc:HGNC:18718]
Ensembl ID
ENSG00000158201
Bio databases IDs NCBI: 171586 Ensembl: ENSG00000158201
Aliases abhydrolase domain containing 3, phospholipase
Synonyms abhydrolase domain containing 3, abhydrolase domain containing 3, phospholipase, LABH3
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ABHD3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alpha/beta hydrolase fold
  • phospholipase A1
  • alpha/beta hydrolases
  • Alpha/beta hydrolase family
  • enzyme
  • phospholipase A2

Pathways

Biological processes and signaling networks where the ABHD3 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • hepatitis B virus
  • HIC1
regulates
  • phosphatidylcholine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ABHD3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phosphatidylcholine metabolic process
  • medium-chain fatty acid biosynthetic process
  • medium-chain fatty acid catabolic process
  • phosphatidylcholine biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • phospholipase A2 activity
  • acylglycerol lipase activity
  • 1-acyl-2-lysophosphatidylserine acylhydrolase activity
  • acetylesterase activity
  • phosphatidylserine 1-acylhydrolase activity
  • phosphatidylcholine 1-acylhydrolase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.