Uck1 Gene Summary [Mouse]
Enables uridine kinase activity. Involved in UMP salvage. Predicted to be active in cytoplasm. Is expressed in nervous system; respiratory system; and urinary system. Orthologous to human UCK1 (uridine-cytidine kinase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Uck1 |
| Official Name | uridine-cytidine kinase 1 [Source:MGI Symbol;Acc:MGI:98904] |
| Ensembl ID | ENSMUSG00000002550 |
| Bio databases IDs | |
| Aliases | uridine-cytidine kinase 1 |
| Synonyms | Umpk, uridine-cytidine kinase 1, Uridine Kinase, URK1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Uck1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- nucleoside kinase
- uridine kinase
- NK
- alcohol group acceptor phosphotransferase
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Uck1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- CTP salvage
- CMP biosynthetic process
- UMP salvage
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- uridine kinase activity
- cytidine kinase activity