Uprt Gene Summary [Mouse]
Predicted to enable ribosylnicotinamide kinase activity and ribosylnicotinate kinase activity. Predicted to be involved in UMP biosynthetic process. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human UPRT (uracil phosphoribosyltransferase homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Uprt |
| Official Name | uracil phosphoribosyltransferase [Source:MGI Symbol;Acc:MGI:2685620] |
| Ensembl ID | ENSMUSG00000073016 |
| Bio databases IDs | |
| Aliases | uracil phosphoribosyltransferase |
| Synonyms | D830012I24Rik, FUR1, Gm774, LOC107985663, RGD1564806, UPP, uracil phosphoribosyltransferase, uracil phosphoribosyltransferase homolog |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Uprt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- uracil phosphoribosyltransferase
- Phosphoribosyl transferase (PRT)-type I domain
- enzyme
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Uprt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to insulin stimulus
- UMP biosynthetic process
- female pregnancy
- lactation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- intracellular membrane-bounded organelle
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- ribosylnicotinamide kinase activity