Fam162a Gene Summary [Mouse]
Involved in several processes, including cellular response to hypoxia; neuron apoptotic process; and positive regulation of release of cytochrome c from mitochondria. Located in mitochondrion. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human FAM162A (family with sequence similarity 162 member A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam162a |
| Official Name | family with sequence similarity 162, member A [Source:MGI Symbol;Acc:MGI:1917436] |
| Ensembl ID | ENSMUSG00000003955 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 162, member A |
| Synonyms | 2310056P07Rik, C3orf28, E2IG5, family with sequence similarity 162 member A, family with sequence similarity 162, member A, HGTD-P |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam162a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function (DUF1075)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam162a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of apoptotic process
- positive regulation of release of cytochrome c from mitochondria
- cellular response to hypoxia
- activation of cysteine-type endopeptidase activity involved in apoptotic process
- neuron apoptotic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding