FAM162A Gene Summary [Human]

Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to hypoxia; and positive regulation of release of cytochrome c from mitochondria. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
FAM162A
Official Name
family with sequence similarity 162 member A [Source:HGNC Symbol;Acc:HGNC:17865]
Ensembl ID
ENSG00000114023
Bio databases IDs NCBI: 26355 Ensembl: ENSG00000114023
Aliases family with sequence similarity 162 member A
Synonyms 2310056P07Rik, C3orf28, E2IG5, family with sequence similarity 162 member A, family with sequence similarity 162, member A, HGTD-P
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FAM162A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Protein of unknown function (DUF1075)
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • alcoholism
regulated by
regulates
role in cell
  • apoptosis
  • permeability transition
  • response by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human FAM162A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of apoptotic process
  • positive regulation of release of cytochrome c from mitochondria
  • cellular response to hypoxia
  • activation of cysteine-type endopeptidase activity involved in apoptotic process
  • neuron apoptotic process

Cellular Component

Where in the cell the gene product is active
  • mitochondrial membrane
  • mitochondrion
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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