Clint1 Gene Summary [Mouse]
Predicted to enable clathrin binding activity and phospholipid binding activity. Predicted to be involved in clathrin coat assembly and endocytosis. Predicted to be located in Golgi apparatus; clathrin-coated vesicle; and nucleoplasm. Predicted to be part of clathrin vesicle coat. Predicted to be active in endosome and plasma membrane. Is expressed in several structures, including craniocervical region bone; respiratory system cartilage; salivary gland primordium; sensory organ; and thoracic segment skeleton. Orthologous to human CLINT1 (clathrin interactor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Clint1 |
| Official Name | clathrin interactor 1 [Source:MGI Symbol;Acc:MGI:2144243] |
| Ensembl ID | ENSMUSG00000006169 |
| Bio databases IDs | |
| Aliases | clathrin interactor 1 |
| Synonyms | AI642036, C530049I24RIK, clathrin interactor 1, CLINT, ENTH, ENTHOPROTIN, EPN4, EPNR, EPSINR, F630206G17Rik, KIAA0171, LOC100131045 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Clint1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nucleoporin FG repeat region
- VHS, ENTH and ANTH domain superfamily
- clathrin binding
- protein binding
- type 2 clathrin box
- ENTH domain
- Clathrin box like domain
Pathways
Biological processes and signaling networks where the Clint1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- intracellular membrane-bounded organelle
- apical compartment
- perinuclear region
- cellular membrane
- endosomes
- vesicles
- Golgi Apparatus
- Mitochondria
- cytoplasmic aggregates
- cytosol
- trans Golgi network
- nucleoplasm
- clathrin-coated vesicles
- vesicle fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Clint1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- clathrin coat assembly
- endocytosis
Cellular Component
Where in the cell the gene product is active
- endosome
- perinuclear region of cytoplasm
- intracellular membrane-bounded organelle
- membrane
- cytosol
- Golgi apparatus
- clathrin vesicle coat
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- cadherin binding
- clathrin binding
- phospholipid binding