Clint1 Gene Summary [Rat]

Enables clathrin binding activity. Involved in clathrin coat assembly. Located in clathrin-coated vesicle. Orthologous to human CLINT1 (clathrin interactor 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Clint1
Official Name
clathrin interactor 1 [Source:RGD Symbol;Acc:1303328]
Ensembl ID
ENSRNOG00000005406
Bio databases IDs NCBI: 360515 Ensembl: ENSRNOG00000005406
Aliases clathrin interactor 1
Synonyms AI642036, C530049I24RIK, clathrin interactor 1, CLINT, ENTH, ENTHOPROTIN, EPN4, EPNR, EPSINR, F630206G17Rik, KIAA0171, LOC100131045
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Clint1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Nucleoporin FG repeat region
  • VHS, ENTH and ANTH domain superfamily
  • clathrin binding
  • protein binding
  • type 2 clathrin box
  • ENTH domain
  • Clathrin box like domain

Pathways

Biological processes and signaling networks where the Clint1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • peripheral arterial disease
regulated by
  • NRP1
  • Influenza A virus (A/Japan/305/57(H2N2))
  • AP1M1
  • OSW-1
  • BMP2K
  • mir-145
regulates
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • membrane fraction
  • intracellular membrane-bounded organelle
  • apical compartment
  • perinuclear region
  • cellular membrane
  • endosomes
  • vesicles
  • Golgi Apparatus
  • Mitochondria
  • cytoplasmic aggregates
  • cytosol
  • trans Golgi network
  • nucleoplasm
  • clathrin-coated vesicles
  • vesicle fraction

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Clint1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • clathrin coat assembly
  • endocytosis

Cellular Component

Where in the cell the gene product is active
  • endosome
  • perinuclear region of cytoplasm
  • intracellular membrane-bounded organelle
  • membrane
  • cytosol
  • Golgi apparatus
  • clathrin vesicle coat
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • cadherin binding
  • clathrin binding
  • phospholipid binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.