Efr3a Gene Summary [Mouse]
Predicted to enable protein homodimerization activity. Involved in synaptic vesicle priming. Located in plasma membrane. Is active in glutamatergic synapse. Is expressed in genitourinary system. Orthologous to human EFR3A (EFR3 homolog A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Efr3a |
| Official Name | EFR3 homolog A [Source:MGI Symbol;Acc:MGI:1923990] |
| Ensembl ID | ENSMUSG00000015002 |
| Bio databases IDs | |
| Aliases | EFR3 homolog A |
| Synonyms | A130089M23Rik, C920006C10Rik, D030063F01Rik, EFR3 homolog A, KIAA0143, mKIAA0143, RGD1305976, TRCP1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Efr3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein homodimerization
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- atopic dermatitis
- Huntington disease
- overall survival
- cerebral amyloid angiopathy
role in cell
- phosphorylation in
- transformation
- priming
- influx in
- JQ1 resistance
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- detergent resistant lipid raft fraction
- glutaminergic synapse
- cornified envelope
- intracellular space
- cellular membrane
- Nucleus
- cytosol
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Efr3a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phosphatidylinositol phosphorylation
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- cytosol
- plasma membrane