Plgrkt Gene Summary [Mouse]
Acts upstream of or within positive regulation of plasminogen activation. Located in plasma membrane. Is expressed in thymus primordium. Orthologous to human PLGRKT (plasminogen receptor with a C-terminal lysine). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Plgrkt |
| Official Name | plasminogen receptor, C-terminal lysine transmembrane protein [Source:MGI Symbol;Acc:MGI:1915009] |
| Ensembl ID | ENSMUSG00000016495 |
| Bio databases IDs | |
| Aliases | plasminogen receptor, C-terminal lysine transmembrane protein |
| Synonyms | 1110007H22Rik, 5033414D02Rik, AD025, C9orf46, MDS030, plasminogen receptor, C-terminal lysine transmembrane protein, plasminogen receptor with a C-terminal lysine, RGD1306839 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Plgrkt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Uncharacterized conserved protein (DUF2368)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insulin-dependent diabetes mellitus
- dermatitis
- COVID-19
- complete testicular feminization syndrome
role in cell
- quantity
- activation in
- invasion
- migration
- recruitment
- binding
- chemotaxis
- function
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell surface
- cellular membrane
- Plasma Membrane
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Plgrkt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chemotaxis
- inflammatory response
- positive regulation of plasminogen activation
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding