Scrn1 Gene Summary [Mouse]
Predicted to enable cysteine-type exopeptidase activity and dipeptidase activity. Predicted to be involved in exocytosis and regulation of synaptic vesicle cycle. Predicted to be located in nuclear membrane. Predicted to be active in presynapse. Is expressed in several structures, including central nervous system; olfactory epithelium; peripheral nervous system ganglion; reproductive system; and retina. Orthologous to human SCRN1 (secernin 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Scrn1 |
| Official Name | secernin 1 [Source:MGI Symbol;Acc:MGI:1917188] |
| Ensembl ID | ENSMUSG00000019124 |
| Bio databases IDs | |
| Aliases | secernin 1 |
| Synonyms | 2810019K23Rik, 6330535A03Rik, mKIAA0193, secernin 1, SES1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Scrn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rotator cuff injury
- psoriasis
- oral squamous cell carcinoma
- squamous cell cancer of the oral cavity
role in cell
- phosphorylation in
- invasion by
- proliferation
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- presynaptic regions
- Nucleus
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Scrn1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- exocytosis
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear membrane
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- dipeptidase activity
- cysteine-type exopeptidase activity