Zfp687 Gene Summary [Mouse]

Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and olfactory epithelium. Human ortholog(s) of this gene implicated in Paget's disease of bone 6. Orthologous to human ZNF687 (zinc finger protein 687). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Zfp687
Official Name
zinc finger protein 687 [Source:MGI Symbol;Acc:MGI:1925516]
Ensembl ID
ENSMUSG00000019338
Bio databases IDs NCBI: 78266 Ensembl: ENSMUSG00000019338
Aliases zinc finger protein 687
Synonyms 4931408L03Rik, KIAA1441, mKIAA1441, PDB6, Zfp687, zinc finger protein 687
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp687 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc finger, C2H2 type
  • transcription regulator
  • zinc-finger C2H2-type
  • protein binding
  • C2H2-type zinc ribbon

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Paget disease of bone 6
regulated by
regulates
role in cell
  • transcription in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp687 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of transcription, DNA-dependent

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • DNA binding
  • sequence-specific DNA binding transcription factor activity
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

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