Vta1 Gene Summary [Mouse]
Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Located in cytoplasm. Is expressed in 1st branchial arch; cortical plate; fronto-nasal process; heart; and limb. Orthologous to human VTA1 (vesicle trafficking 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Vta1 |
| Official Name | vesicle (multivesicular body) trafficking 1 [Source:MGI Symbol;Acc:MGI:1913451] |
| Ensembl ID | ENSMUSG00000019868 |
| Bio databases IDs | |
| Aliases | vesicle (multivesicular body) trafficking 1 |
| Synonyms | 1110001D18Rik, 1110059P08Rik, 6orf55, C6orf55, C85340, DRG-1, HSPC228, LIP5, My012, RGD1305031, SBP1, vesicle (multivesicular body) trafficking 1, vesicle trafficking 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Vta1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Vta1 like
- Vta1 C-terminal domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- intracellular membrane-bounded organelle
- Cytoplasm
- intracellular space
- apical compartment
- Plasma Membrane
- cytosol
- apical membrane
- nucleoplasm
- perinuclear vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Vta1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- multivesicular body sorting pathway
- macroautophagy
- late endosome to vacuole transport via multivesicular body sorting pathway
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- intracellular membrane-bounded organelle
- cytosol
- endosome membrane
- multivesicular body
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding