Fabp7 Gene Summary [Mouse]
Predicted to enable fatty acid binding activity. Acts upstream of or within cell proliferation in forebrain; neurogenesis; and prepulse inhibition. Located in several cellular components, including cell projection; cell-cell junction; and neuronal cell body. Is expressed in several structures, including central nervous system; gut; olfactory system; peripheral nervous system; and retina. Orthologous to human FABP7 (fatty acid binding protein 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fabp7 |
| Official Name | fatty acid binding protein 7, brain [Source:MGI Symbol;Acc:MGI:101916] |
| Ensembl ID | ENSMUSG00000019874 |
| Bio databases IDs | |
| Aliases | fatty acid binding protein 7, brain |
| Synonyms | B-FABP, BLBP, Brain fatty acid binding, FABPB, fatty acid binding protein 7, fatty acid binding protein 7, brain, MRG |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fabp7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid binding
- lipocalin/cytosolic fatty acid-binding protein family
- fatty acid binding
- protein binding
- Lipocalin / cytosolic fatty-acid binding protein family
- transporter
Pathways
Biological processes and signaling networks where the Fabp7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- astrocytoma
- glioma formation
- oligodendroglioma
- organismal death
- psoriasis
- oligoastrocytoma
- prostate cancer
- epithelial cancer
- insulin-dependent diabetes mellitus
- senile lentigo
role in cell
- proliferation
- migration
- growth
- cell death
- differentiation
- cell viability
- outgrowth
- cytostasis
- growth in
- suppression in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- detergent resistant lipid raft fraction
- cell periphery
- Nucleus
- intercellular junctions
- cytosol
- growth cone
- cellular protrusions
- membrane processes
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fabp7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- epithelial cell proliferation
- fatty acid transport
- negative regulation of cell proliferation
- nervous system development
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- fatty acid binding
- protein binding
- lipid binding