Map7 Gene Summary [Mouse]
Enables signaling receptor binding activity. Involved in protein localization to plasma membrane and response to osmotic stress. Acts upstream of or within several processes, including glycosphingolipid metabolic process; male gonad development; and response to retinoic acid. Located in plasma membrane. Is expressed in several structures, including alimentary system; endocrine gland; genitourinary system; nervous system; and skin. Orthologous to human MAP7 (microtubule associated protein 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Map7 |
| Official Name | microtubule-associated protein 7 [Source:MGI Symbol;Acc:MGI:1328328] |
| Ensembl ID | ENSMUSG00000019996 |
| Bio databases IDs | |
| Aliases | microtubule-associated protein 7 |
| Synonyms | E-MAP-115, ENSCONSIN, microtubule-associated protein 7, mshi, mste, Mtap7, Mtap7 predicted, ste |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Map7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MAP7 (E-MAP-115) family
- coiled-coil domain
- protein binding
- receptor binding
- structural molecule
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung cancer
- acute myeloid leukemia
- oral squamous cell carcinoma
- squamous cell cancer of the oral cavity
- glioblastoma
- glioblastoma cancer
- hepatitis B
role in cell
- proliferation
- quantity
- differentiation
- branching
- morphogenesis
- formation
- development
- stability
- branching in
- organization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule aster fraction
- microtubule cytoskeleton
- Plasma Membrane
- vesicles
- microtubules
- cytosol
- basolateral membrane
- axons
- axon terminals
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Map7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- establishment or maintenance of cell polarity
- response to osmotic stress
- microtubule cytoskeleton organization
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- perinuclear region of cytoplasm
- cytosol
- basolateral plasma membrane
- axon
- microtubule associated complex
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding
- structural molecule activity
- receptor binding