Llph Gene Summary [Mouse]
Enables basal RNA polymerase II transcription machinery binding activity. Involved in dendrite extension and positive regulation of dendritic spine development. Located in nucleolus. Orthologous to human LLPH (LLP homolog, long-term synaptic facilitation factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Llph |
| Official Name | LLP homolog, long-term synaptic facilitation (Aplysia) [Source:MGI Symbol;Acc:MGI:1913475] |
| Ensembl ID | ENSMUSG00000020224 |
| Bio databases IDs | |
| Aliases | LLP homolog, long-term synaptic facilitation (Aplysia) |
| Synonyms | 1190005P17Rik, C12orf31, hLLP, LLP homolog, long-term synaptic facilitation (Aplysia), LLP homolog, long-term synaptic facilitation factor, LOC100360837, RGD1308261 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Llph often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Learning-associated protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromosome
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Llph gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of dendritic spine development
Cellular Component
Where in the cell the gene product is active
- chromosome
- nucleolus
Molecular Function
What the gene product does at the molecular level
- basal RNA polymerase II transcription machinery binding
- RNA binding
- protein binding