Srsf12 Gene Summary [Mouse]
Predicted to be involved in mRNA 5'-splice site recognition and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Orthologous to human SRSF12 (serine and arginine rich splicing factor 12). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Srsf12 |
| Official Name | serine and arginine-rich splicing factor 12 [Source:MGI Symbol;Acc:MGI:2661424] |
| Ensembl ID | ENSMUSG00000054679 |
| Bio databases IDs | |
| Aliases | serine and arginine-rich splicing factor 12 |
| Synonyms | B830039L16, RGD1561162, serine and arginine-rich splicing factor 12, SFRS13B, SFRS19, Srrp, SRrp35, Srsf13b |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Srsf12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Srsf12 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA 5'-splice site recognition
- regulation of alternative nuclear mRNA splicing, via spliceosome
- negative regulation of nuclear mRNA splicing, via spliceosome
- nuclear mRNA splicing, via spliceosome
- assembly of spliceosomal tri-snRNP
Cellular Component
Where in the cell the gene product is active
- nuclear speck
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- unfolded protein binding
- RS domain binding