Rpl30 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; defense response to other organism; and killing of cells of another organism. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in postsynaptic density. Is expressed in brain. Human ortholog(s) of this gene implicated in herpes simplex. Orthologous to human RPL30 (ribosomal protein L30). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl30 |
| Official Name | ribosomal protein L30 [Source:MGI Symbol;Acc:MGI:98037] |
| Ensembl ID | ENSMUSG00000058600 |
| Bio databases IDs | |
| Aliases | ribosomal protein L30 |
| Synonyms | eL30, L30, ribosomal protein L30 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl30 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
- mRNA binding
- protein binding
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl30 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Nucleus
- cytosol
- nucleoli
- synapse
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl30 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to Gram-negative bacterium
- cytoplasmic translation
- killing of cells of other organism
- translation
Cellular Component
Where in the cell the gene product is active
- postsynaptic density
- nucleus
- extracellular vesicular exosome
- cytosolic ribosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
- cytosolic large ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome