Wdr82 Gene Summary [Mouse]
Enables chromatin binding activity and lncRNA binding activity. Involved in RNA catabolic process and negative regulation of DNA-templated transcription. Acts upstream of or within gene expression. Located in nucleus. Is expressed in early conceptus and ovary. Orthologous to human WDR82 (WD repeat domain 82). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr82 |
| Official Name | WD repeat domain containing 82 [Source:MGI Symbol;Acc:MGI:1924555] |
| Ensembl ID | ENSMUSG00000020257 |
| Bio databases IDs | |
| Aliases | WD repeat domain containing 82 |
| Synonyms | 9430077D24Rik, CDW5/WDR82, MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A, WD repeat domain 82, WD repeat domain containing 82 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr82 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- WD40
- chromatin binding
- protein binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
- telomeres
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr82 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription elongation, DNA-dependent
- transcription termination, DNA-dependent
- nuclear RNA surveillance
Cellular Component
Where in the cell the gene product is active
- Set1C/COMPASS complex
- chromosome, telomeric region
- histone methyltransferase complex
- PTW/PP1 phosphatase complex
- nucleolus
- chromatin
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- chromatin binding