Tspan13 Gene Summary [Mouse]

Enables calcium channel regulator activity. Acts upstream of or within regulation of calcium ion transmembrane transport. Located in plasma membrane. Is expressed in several structures, including cerebral cortex; ganglia; genitourinary system; gut; and lung. Orthologous to human TSPAN13 (tetraspanin 13). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tspan13
Official Name
tetraspanin 13 [Source:MGI Symbol;Acc:MGI:1913359]
Ensembl ID
ENSMUSG00000020577
Bio databases IDs NCBI: 66109 Ensembl: ENSMUSG00000020577
Aliases tetraspanin 13
Synonyms 1100001I23Rik, NET-6, tetraspanin 13, TM4SF13
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tspan13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • calcium channel regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • non-insulin-dependent diabetes mellitus
  • breast adenocarcinoma
  • hypertrophic scarring
  • Rett syndrome
regulated by
regulates
  • Ca2+
  • cyclic AMP
role in cell
  • accumulation in
  • osteoclastogenesis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tspan13 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • calcium channel regulator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.