Amz2 Gene Summary [Mouse]

Predicted to enable metal ion binding activity and metallopeptidase activity. Predicted to be involved in proteolysis. Is expressed in several structures, including central nervous system; heart ventricle; and sensory organ. Orthologous to human AMZ2 (archaelysin family metallopeptidase 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Amz2
Official Name
archaelysin family metallopeptidase 2 [Source:MGI Symbol;Acc:MGI:104837]
Ensembl ID
ENSMUSG00000020610
Bio databases IDs NCBI: 13929 Ensembl: ENSMUSG00000020610
Aliases archaelysin family metallopeptidase 2
Synonyms AA408420, archaelysin family metallopeptidase 2, ESTM12, RGD1304846
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Amz2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ZnMc

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • cisplatin
  • levodopa
  • mir-483
  • RBM39

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Amz2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • metallopeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.