Rbm39 Gene Summary [Mouse]
Enables RS domain binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be located in centriolar satellite and nuclear speck. Predicted to be part of protein-containing complex. Is expressed in several structures, including central nervous system; genitourinary system; limb; olfactory epithelium; and retina. Orthologous to human RBM39 (RNA binding motif protein 39). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rbm39 |
| Official Name | RNA binding motif protein 39 [Source:MGI Symbol;Acc:MGI:2157953] |
| Ensembl ID | ENSMUSG00000027620 |
| Bio databases IDs | |
| Aliases | RNA binding motif protein 39 |
| Synonyms | 1500012C14Rik, 2310040E03Rik, B330012G18RIK, C79248, CAPER, CAPERalpha, FSAP59, HCC1, LOC100910882, RNA binding motif protein 39, Rnp1, RNPC2, Rrm, Similar to i55595 splicing factor |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rbm39 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UHM domain
- RNA recognition motif (RRM) superfamily
- RS domain binding
- transcription regulator
- RNA recognition motif
- splicing factor, CC1-like family
- linker between RRM2 and RRM3 domains in RBM39 protein
- Occluded RNA-recognition motif
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- osteoarthritis
- ischemic stroke
- infiltrating ductal breast carcinoma
- invasive ductal breast cancer
- intrauterine growth retardation
- breast ductal carcinoma in situ
- ductal in situ breast cancer
role in cell
- expression in
- cell death
- degradation in
- cell viability
- growth
- proliferation
- migration
- ubiquitination in
- invasion by
- colony formation by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- polyribosome fractions
- microtubule cytoskeleton
- Cytoplasm
- centrosome
- spliceosomes
- nucleoplasm
- interchromatin granule clusters
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rbm39 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- regulation of nuclear mRNA splicing, via spliceosome
- RNA processing
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- centriolar satellite
- nuclear speck
- macromolecular complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- RS domain binding