Cep112 Gene Summary [Mouse]
Predicted to act upstream of or within receptor localization to synapse. Predicted to be located in centrosome; inhibitory synapse; and plasma membrane. Human ortholog(s) of this gene implicated in spermatogenic failure 44. Orthologous to human CEP112 (centrosomal protein 112). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep112 |
| Official Name | centrosomal protein 112 [Source:MGI Symbol;Acc:MGI:1923673] |
| Ensembl ID | ENSMUSG00000020728 |
| Bio databases IDs | |
| Aliases | centrosomal protein 112 |
| Synonyms | 1700001M19RIK, 1700029K01Rik, 8430407H02Rik, CCDC46, centrosomal protein 112, MACOCO, RGD1564168, SPGF44 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cep112 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- chromosome segregation protein SMC, common bacterial type
- RIM-binding protein of the cytomatrix active zone
- chromosome segregation protein SMC, primarily archaeal type
- exonuclease SbcC
- Synaptonemal complex protein 1 (SCP-1)
- Domain of unknown function (DUF4485)
- helix-rich Mycoplasma protein
- protein binding
- Calcium binding and coiled-coil domain (CALCOCO1) like
- Septation ring formation regulator, EzrA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- centrosome
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cep112 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- receptor localization to synapse
Cellular Component
Where in the cell the gene product is active
- inhibitory synapse
- centrosome
- cytoplasm
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding