Gkap1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Involved in positive regulation of insulin receptor signaling pathway and signal transduction. Located in Golgi apparatus. Is expressed in several structures, including aorta; genitourinary system; gut gland; nervous system; and trachea. Orthologous to human GKAP1 (G kinase anchoring protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gkap1 |
| Official Name | G kinase anchoring protein 1 [Source:MGI Symbol;Acc:MGI:1891694] |
| Ensembl ID | ENSMUSG00000021552 |
| Bio databases IDs | |
| Aliases | G kinase anchoring protein 1 |
| Synonyms | 4933400B15Rik, D13Ertd340e, FKSG21, GKAP42, G kinase anchoring protein 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gkap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- coiled-coil domain
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gkap1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of insulin receptor signaling pathway
- signal transduction
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding