Dcp1a Gene Summary [Mouse]
Predicted to enable identical protein binding activity; kinesin binding activity; and mRNA binding activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA; deadenylation-independent decapping of nuclear-transcribed mRNA; and protein localization to cytoplasmic stress granule. Predicted to act upstream of or within positive regulation of DNA-templated transcription and transforming growth factor beta receptor signaling pathway. Located in P-body. Is expressed in several structures, including genitourinary system; limb; liver; muscle tissue; and spleen. Orthologous to human DCP1A (decapping mRNA 1A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Dcp1a |
| Official Name | decapping mRNA 1A [Source:MGI Symbol;Acc:MGI:1923151] |
| Ensembl ID | ENSMUSG00000021962 |
| Bio databases IDs | |
| Aliases | decapping mRNA 1A |
| Synonyms | 1110066A22Rik, 4930568L04Rik, D14Ertd817e, decapping mRNA 1A, HSA275986, Mitc1, Nbla00360, RGD1561298, SMAD4IP1, SMIF |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dcp1a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dcp1-like decapping family
- transcription factor binding
- protein binding
- Pleckstrin homology-like domain
- identical protein binding
- kinesin binding
- mRNA-decapping enzyme C-terminus
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- GW body
- cytoplasmic ribonucleoprotein granule
- cytoplasmic mRNA processing body
- Cytoplasm
- cytoplasmic aggregates
- cytosol
- sister chromatids
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dcp1a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
- deadenylation-independent decapping of nuclear-transcribed mRNA
- deadenylation-dependent decapping of nuclear-transcribed mRNA
Cellular Component
Where in the cell the gene product is active
- nucleus
- dendrite
- cytoplasm
- membrane
- cytosol
- cytoplasmic mRNA processing body
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- kinesin binding
- mRNA binding
- enzyme activator activity