Dnal4 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Predicted to be involved in microtubule-based process. Predicted to be located in cilium; cytoplasm; and microtubule. Predicted to be part of dynein complex. Is expressed in central nervous system; heart ventricle; and retina. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Orthologous to human DNAL4 (dynein axonemal light chain 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dnal4 |
| Official Name | dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217] |
| Ensembl ID | ENSMUSG00000022420 |
| Bio databases IDs | |
| Aliases | dynein, axonemal, light chain 4 |
| Synonyms | D15Ertd424e, Dnalc4, dynein axonemal light chain 4, dynein, axonemal, light chain 4, MRMV3, PIG27 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dnal4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PLN03058
- Dynein light chain type 1
- dynein light chain (DLC)-like domain superfamily
- enzyme
- protein binding
- identical protein binding
- microtubule motor protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dnal4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule-based movement
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- dynein complex
- cilium
- plasma membrane
- microtubule
Molecular Function
What the gene product does at the molecular level
- microtubule motor activity
- identical protein binding
- protein binding