Endou Gene Summary [Mouse]
Predicted to enable RNA binding activity; RNA endonuclease activity; and serine-type peptidase activity. Predicted to be involved in female pregnancy; negative regulation of metabolic process; and proteolysis. Predicted to be located in cytoplasm. Is expressed in ileum; labyrinthine zone; and metanephros. Orthologous to human ENDOU (endonuclease, poly(U) specific). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Endou |
| Official Name | endonuclease, polyU-specific [Source:MGI Symbol;Acc:MGI:97746] |
| Ensembl ID | ENSMUSG00000022468 |
| Bio databases IDs | |
| Aliases | endonuclease, polyU-specific |
| Synonyms | endonuclease, poly(U)-specific, endonuclease, polyU-specific, LOC682220, P11, PP11, Pp11r, PRSS26, Tcl-30 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Endou often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NendoU_XendoU-like
- serine-type peptidase
- peptidase
- endoribonuclease
- Endoribonuclease XendoU
- manganese ion binding
- Somatomedin B domain
- RNA binding
Pathways
Biological processes and signaling networks where the Endou gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum tubules
- Extracellular Space
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Endou gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- immune response
- vesicle-mediated transport
- signal transduction
- proteolysis
- female pregnancy
- posttranscriptional gene silencing
- negative regulation of lipid catabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytoplasm
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- growth factor activity
- RNA binding
- scavenger receptor activity
- serine-type peptidase activity
- lyase activity
- manganese ion binding
- polysaccharide binding
- endoribonuclease activity