Prxl2a Gene Summary [Mouse]
Predicted to enable antioxidant activity. Predicted to be involved in regulation of osteoclast differentiation. Located in mitochondrion. Is expressed in several structures, including alimentary system; ganglia; lung; sensory organ; and urinary system. Orthologous to human PRXL2A (peroxiredoxin like 2A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prxl2a |
| Official Name | peroxiredoxin like 2A [Source:MGI Symbol;Acc:MGI:1917814] |
| Ensembl ID | ENSMUSG00000021792 |
| Bio databases IDs | |
| Aliases | peroxiredoxin like 2A |
| Synonyms | 5730469M10Rik, Adrx, C10orf58, FAM213A, MGC4248, PAMM, peroxiredoxin like 2A, RGD1309676 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prxl2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- AhpC/TSA antioxidant enzyme
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- antioxidant enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prxl2a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of osteoclast differentiation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- extracellular region
Molecular Function
What the gene product does at the molecular level
- antioxidant activity