Chodl Gene Summary [Mouse]
Predicted to enable carbohydrate binding activity. Acts upstream of or within regulation of neuron projection development. Predicted to be located in centrosome; cytosol; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and respiratory system. Orthologous to human CHODL (chondrolectin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Chodl |
| Official Name | chondrolectin [Source:MGI Symbol;Acc:MGI:2179069] |
| Ensembl ID | ENSMUSG00000022860 |
| Bio databases IDs | |
| Aliases | chondrolectin |
| Synonyms | 3110074E07Rik, C21orf68, Chondrolectin, MT75, PRED12 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Chodl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- major depression
- cataract
- rheumatic carditis
- idiopathic scoliosis
- neuroblastoma
- neuroblastoma formation
- aortic valve calcification
- sporadic amyotrophic lateral sclerosis
- bulimia nervosa
role in cell
- development
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- perinuclear region
- cellular membrane
- centrosome
- ER-to-Golgi intermediate compartment
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Chodl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- muscle organ development
- positive regulation of axonogenesis
- nervous system development
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- centrosome
- perinuclear region of cytoplasm
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- hyaluronic acid binding
- carbohydrate binding