Snx16 Gene Summary [Mouse]
Predicted to enable identical protein binding activity and phosphatidylinositol binding activity. Predicted to be involved in early endosome to late endosome transport; lysosomal transport; and receptor recycling. Predicted to be located in endosome membrane. Predicted to be active in early endosome and late endosome. Orthologous to human SNX16 (sorting nexin 16). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snx16 |
| Official Name | sorting nexin 16 [Source:MGI Symbol;Acc:MGI:1921968] |
| Ensembl ID | ENSMUSG00000027534 |
| Bio databases IDs | |
| Aliases | sorting nexin 16 |
| Synonyms | 4930522N22Rik, sorting nexin 16 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Snx16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- coiled-coil domain
- The Phox Homology domain, a phosphoinositide binding module
- identical protein binding
- phosphatidylinositol binding
- PX domain
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- endosomal membrane
- early endosomes
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Snx16 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- early endosome to late endosome transport
- endosome to lysosome transport
- protein targeting to lysosome
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- late endosome membrane
- early endosome
- intracellular membrane-bounded organelle
- late endosome
- endosome membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- phosphatidylinositol binding