Ube2o

Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of BMP signaling pathway; protein ubiquitination; and retrograde transport, endosome to Golgi. Predicted to be located in cytoplasm and nuclear body. Is expressed in several structures, including alimentary system; central nervous system; connective tissue; genitourinary system; and immune system. Orthologous to human UBE2O (ubiquitin conjugating enzyme E2 O). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ube2o often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ube2o gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ube2o gene, providing context for its role in the cell.