LUC7L Gene Summary [Human]
The LUC7L gene may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection (Tufarelli et al., 2001 [PubMed 11170747]).[supplied by OMIM, Mar 2008]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | LUC7L |
| Official Name | LUC7 like [Source:HGNC Symbol;Acc:HGNC:6723] |
| Ensembl ID | ENSG00000007392 |
| Bio databases IDs | |
| Aliases | LUC7 like |
| Synonyms | 1810045C04Rik, 2410018D03Rik, hLuc7B1, LOC100360956, Luc7, LUC7B1, Luc7l1, LUC7-like, Polybinding protein, cytoplasmic 1, SR+89 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LUC7L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RS domain binding
- LUC7 N_terminus
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LUC7L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA splice site selection
- negative regulation of striated muscle tissue development
Cellular Component
Where in the cell the gene product is active
- U2-type prespliceosome
- U1 snRNP
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- mRNA binding
- RS domain binding