Srfbp1 Gene Summary [Mouse]
Predicted to be involved in maturation of SSU-rRNA. Located in nucleus. Is expressed in several structures, including axial musculature; genitourinary system; neural ectoderm; orbito-sphenoid; and submandibular gland primordium. Orthologous to human SRFBP1 (serum response factor binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Srfbp1 |
| Official Name | serum response factor binding protein 1 [Source:MGI Symbol;Acc:MGI:1914472] |
| Ensembl ID | ENSMUSG00000024528 |
| Bio databases IDs | |
| Aliases | serum response factor binding protein 1 |
| Synonyms | 2810036K01Rik, BUD22, FLJ25286, LOC636713, P49, p49/STRAP, Rlb1, serum response factor binding protein 1, STRAP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Srfbp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- BUD22
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Srfbp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
Cellular Component
Where in the cell the gene product is active
- nucleus
- perinuclear region of cytoplasm
- 90S preribosome
Molecular Function
What the gene product does at the molecular level
- RNA binding