SRFBP1 Gene Summary [Human]
Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of 90S preribosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SRFBP1 |
| Official Name | serum response factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26333] |
| Ensembl ID | ENSG00000151304 |
| Bio databases IDs | |
| Aliases | serum response factor binding protein 1, BUD22 homolog (S. cerevisiae) |
| Synonyms | 2810036K01Rik, BUD22, FLJ25286, LOC636713, P49, p49/STRAP, Rlb1, serum response factor binding protein 1, STRAP |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SRFBP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- BUD22
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SRFBP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
Cellular Component
Where in the cell the gene product is active
- nucleus
- perinuclear region of cytoplasm
- 90S preribosome
Molecular Function
What the gene product does at the molecular level
- RNA binding