SAC3D1 Gene Summary [Human]
Predicted to be involved in centrosome duplication and spindle assembly. Predicted to act upstream of or within negative regulation of receptor signaling pathway via JAK-STAT and regulation of immune response. Predicted to be located in microtubule cytoskeleton. Predicted to be active in centrosome; nucleus; and spindle. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SAC3D1 |
| Official Name | SAC3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30179] |
| Ensembl ID | ENSG00000168061 |
| Bio databases IDs | |
| Aliases | SAC3 domain containing 1 |
| Synonyms | 2410004C24Rik, HSU79266, RGD1308049, SAC3 domain containing 1, SHD1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SAC3D1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SAC3/GANP family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- spindle apparatus
- Nucleus
- centrosome
- midbody
- spindle pole
- mitotic spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SAC3D1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- spindle assembly
- centrosome duplication
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cytoplasm
- spindle
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- protein binding