Arhgap19 Gene Summary [Mouse]
Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including gut; male reproductive gland or organ; and trigeminal nerve. Orthologous to human ARHGAP19 (Rho GTPase activating protein 19). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Arhgap19 |
| Official Name | Rho GTPase activating protein 19 [Source:MGI Symbol;Acc:MGI:1918335] |
| Ensembl ID | ENSMUSG00000025154 |
| Bio databases IDs | |
| Aliases | Rho GTPase activating protein 19 |
| Synonyms | 4933411B03RIK, AI120128, AW546831, mFLJ00368, Rho GTPase activating protein 19 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Arhgap19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RhoGAP domain
- GTPase activator
- protein binding
- GTPase-activator protein for Rho-like GTPases
- RhoGAP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Arhgap19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- regulation of small GTPase mediated signal transduction
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- intracellular membrane-bounded organelle
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- GTPase activator activity