Tro Gene Summary [Mouse]
Acts upstream of or within negative regulation of cell growth. Located in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; early conceptus; limb; and secondary oocyte. Orthologous to human TRO (trophinin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tro |
| Official Name | trophinin [Source:MGI Symbol;Acc:MGI:1928994] |
| Ensembl ID | ENSMUSG00000025272 |
| Bio databases IDs | |
| Aliases | trophinin |
| Synonyms | MAGE-d3, Maged3l, magphinin, Tnn, Trol, trophinin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tro often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mechanosensitive ion channel porin domain
- MAGE homology domain
- nuclear localization sequence
- protein binding
- Keratin type II head
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- Nucleus
- Plasma Membrane
- apical membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tro gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
- homophilic cell adhesion
- embryo implantation
Cellular Component
Where in the cell the gene product is active
- nucleus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding