Mbd6 Gene Summary [Mouse]
Predicted to enable chromatin binding activity. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be active in chromocenter and nucleus. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in autism spectrum disorder. Orthologous to human MBD6 (methyl-CpG binding domain protein 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Mbd6 |
| Official Name | methyl-CpG binding domain protein 6 [Source:MGI Symbol;Acc:MGI:106378] |
| Ensembl ID | ENSMUSG00000025409 |
| Bio databases IDs | |
| Aliases | methyl-CpG binding domain protein 6 |
| Synonyms | D10WSU93E, KIAA1887, LOC102553371, methyl-CpG binding domain protein 6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mbd6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- chromatin binding
- protein binding
- MBD
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- fibrillar center
- chromosome
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mbd6 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- chromocenter
- chromosome
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- chromatin binding