Ppil3 Gene Summary [Mouse]

Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human PPIL3 (peptidylprolyl isomerase like 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ppil3
Official Name
peptidylprolyl isomerase (cyclophilin)-like 3 [Source:MGI Symbol;Acc:MGI:1917475]
Ensembl ID
ENSMUSG00000026035
Bio databases IDs NCBI: 70225 Ensembl: ENSMUSG00000026035
Aliases peptidylprolyl isomerase (cyclophilin)-like 3
Synonyms 2310076N22RIK, 2510026K04Rik, CYP10L, CYPJ, peptidylprolyl isomerase (cyclophilin)-like 3, peptidylprolyl isomerase like 3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppil3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • peptidylprolyl isomerase
  • Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
  • cyclophilin
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • IgA nephropathy
  • epithelial basal cell carcinoma
  • estrogen receptor-negative breast cancer
regulated by
  • DAP3
  • methylprednisolone
  • MYC
  • anandamide
  • NOMO
  • UT-143

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • catalytic step 2 spliceosome
  • spliceosomes
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppil3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein peptidyl-prolyl isomerization
  • protein folding
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • catalytic step 2 spliceosome
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • peptidyl-prolyl cis-trans isomerase activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.