Mitd1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity; phosphatidylinositol binding activity; and protein domain specific binding activity. Predicted to be involved in midbody abscission. Predicted to be located in intracellular membrane-bounded organelle and membrane. Predicted to colocalize with midbody. Orthologous to human MITD1 (microtubule interacting and trafficking domain containing 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mitd1 |
| Official Name | MIT, microtubule interacting and transport, domain containing 1 [Source:MGI Symbol;Acc:MGI:1916278] |
| Ensembl ID | ENSMUSG00000026088 |
| Bio databases IDs | |
| Aliases | MIT, microtubule interacting and transport, domain containing 1 |
| Synonyms | 1500032H18Rik, microtubule interacting and trafficking domain containing 1, MIT, microtubule interacting and transport, domain containing 1, RGD1307700 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mitd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Microtubule Interacting and Trafficking molecule domain
- MIT (microtubule interacting and transport) domain
- MIT
- protein domain specific binding
- protein binding
- MIT_C
- identical protein binding
- phosphatidylinositol binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- cellular membrane
- midbody
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mitd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytokinesis after mitosis
- multivesicular body sorting pathway
- negative regulation of protein binding
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- extracellular vesicular exosome
- intracellular membrane-bounded organelle
- membrane
- midbody
Molecular Function
What the gene product does at the molecular level
- protein domain specific binding
- identical protein binding
- protein binding
- phosphatidylinositol binding